Tuesday, March 30, 2004

Pharmaceutical Industry, Amination

Two important methods of amination (the process of adding an amino (-NH2) group to a compound) are reduction and ammonolysis. There are many reduction methods, but the most common is the reduction of the corresponding nitro compound by means of iron and acid. An example of ammonolysis is the preparation of aniline by heating chlorobenzene with excess aqueous ammonia,

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